Matrix is shocked when he finds Mainframe inside a game cube. Dot is there... Phong is there... even Bob! But why did he and AndrAIa reboot as Megabyte and Hexadecimal? And who is Number One?
Emma and Frank investigate the mysterious biological research conducted by a former Millennium Group member who is dying from a mysterious disease.
An ex-cop is released from jail and seeks revenge on Caitlin who put him there. Nash teams up with Caitlin to capture him. Joe and Inger continue their efforts to become pregnant, discovering how difficult it is. Harvey and Evan go underground as wealthy conventioneers at a ritzy hotel bar to catch a follow-home robber.
A wary Syd tries to do the right thing when she takes in Lilly , a troublesome teenager who is returned by her latest foster parents, but in no time, the lodger's carelessness places the entire Hansen household in jeopardy. Joanie's hopes soar when she learns that her handsome business partner has broken up with his girlfriend, but their main concern however, is finding a restaurant that will let them showcase her special chowder for food distributors. Robbie comes to the rescue and risks his job when he volunteers his place of employment while the owner is away. In addition, Sydney encounters a likable elderly patient (guest star Maxine Stuart) with hidden health problems, and Jim wants to help a bedraggled stray dog give birth to her pups.
A detective for a police agency is teamed with a naive new officer, who is secretly an android, and often conflicts with the Assessor's Office and the security forces of "the Consortium", a small number of extremely powerful companies.
Mona Bailey (Jane Adams) lives with her husband Ned (Peter Outerbridge) in the Clackson Arms, an old apartment building that is being taken over, apartment by apartment, by a mysterious developer called KM Inc. Mona is a hypochondriac, an able-bodied woman who rides a wheelchair, who treats the Physician's Desk Reference like a personal bible and who has not left the building in six months for fear of catching a disease. One day she backs her wheelchair into an electrical box and gets a shock, leaving her hearing strange voices and seeing bodies dropping out of windows...
With nearly a month until their next slide, the Sliders find themselves extremely bored on a dull world. While the others get jobs, Rembrandt dives into a sci-fi book that bears more than a resemblance to their lives. When the Sliders track down the author, they learn he came from Quinn and Colin's home world.
The group arrive on Navel Island where Ash finds himself up against the Gym Leader, Danny as Ash competes for his second Orange League badge. Misty tries to tempt Ash by showing more caring attitude to Danny. Ash once again gets jealous and sad.
Jandra is seriously injured, but the group needs to press on with their journey. Their progress is blocked by an unfordable river, but Hild leads her new friends to medical facilities, and into danger.
Matrix and AndrAIa find themselves on different sides of a conflict between the mysterious Spectrols and a team of super hero sprites.
As Joey's Italian-speaking grandmother visits to watch him on TV, Ross has trouble flirting with the pizza delivery girl, and Rachel tries to find an earring of Monica's that she has misplaced.
The crew visits a planet full of happy workers. Soon D'Argo and Zhaan start working and refuse to return to the ship. Meanwhile Rygel's body fluids become explosive and Aeryn and Pilot must learn why before Rygel dies.
Kyle and Stan try to rescue Chef from the clutches of the Succubus that he is going to marry. Meanwhile, Cartman deals with his eye problems and the optometrist he doesn't like. Chef's Mama and Papa appear for the first time.
Norm goes drinking with a client and wakes up in rehab. He finds out that if he's an alcoholic he has less work to do so he fakes being an alcoholic. When he's asked to give a speech he exposes his lie.
After getting stuck in a game, Matrix, the hardened and cynical warrior once known as Enzo, and AndrAIa have been wandering the net for a very long time, moving from system to system through the games, searching for a way back to Mainframe. This time they arrive in a barely functioning system, devastated by virals and constant lost games.
Kelly and Dylan run into each other at the market and share a cup of coffee. They subdue a man who tries to attack a pregnant woman and her child, and help the woman get to the hospital to have her baby. When the press approaches Kelly, she identifies Steve as the hero because she and Dylan don't want to admit that they were together. Steve initially relishes the attention, but soon suffers from a guilty conscience. He confronts Kelly and Dylan and states that everyone can tell that they want each other. Kelly plans to tell Matt the truth, while Dylan considers breaking up with Gina. Gina receives an offer to become a skating commentator, but loses the job (partially because of Matt's hardball negotiating technique). Matt apologizes and offers Gina work as his assistant. Dylan cannot bring himself to break up with Gina while she is in this vulnerable state. Kelly tells Matt that Dylan was the hero, but stops short of disclosing the fact that she slept with Dylan in Mexico. Noah reveals
Will Truman and Grace Adler are best friends living in New York, and when Grace's engagement falls apart, she moves in with Will. Together, along with their friends, they go through the trials of dating, sex, relationships and their careers, butting heads at times but ultimately supporting one another while exchanging plenty of witty banter along the way.
After a philosophy professor is pushed in front of a subway and killed, the investigation leads to a suspect who, following a divorce, changed his identity and disappeared with his daughters.